Health Economics Manager

AstraZeneca UK

Location: Greater London

Job Type: Full time


Health Economics Manager


Competitive salary and package

Closing Date: 16th February 2023

Do you have expertise in and passion for access submissions? Would you like to apply your expertise in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

As a Health Economics Manager, you’ll lead the delivery of health economic content for HTA submissions to convey the value of AstraZeneca medicines, with the aim of securing national level patient access, for Biopharmaceutical Business Unit Cardiovascular, Renal & Metabolic (CVRM) products.

At AstraZeneca UK, we bring life-changing medicines to patients across England, Scotland, Wales and Northern Ireland. As a member of the Association of the British Pharmaceutical Industry (ABPI), all of our sales, marketing and communications activities are subject to the ABPI Code of Practice.

Our move to Pancras Square offers us the strongest possible platform to transform the lives of patients as the country’s leading biopharmaceutical company. It will bring AstraZeneca UK closer to our customers, partners and stakeholders in the UK’s healthcare environment, as well as foster greater collaboration with the wider AstraZeneca footprint.

Business Area

AstraZeneca is a global, innovation-driven BioPharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases.

In Market Access, we’re always innovating to offer better solutions: finding ways to get involved earlier, building value-based arrangements, adapting to different payer requirements and changing engagement rules.

A crucial role in the business, we look to the future, analysing trends and spotting opportunities. This shapes the advice we offer, as we translate it into strategic and technical actions across the enterprise.

We make sure our access is right for both patients and AstraZeneca, allowing us to gain value and reinvest for a brighter future.

What you’ll do:

Develop, tailor and deliver health economic analyses for health technology appraisals:

  • Work in conjunction with global HEOR function to shape the development of cost utility analysis models, systematic literature reviews, network meta-analyses and other payer-related materials for HTA

  • Provide strategic input into pricing strategy, evidence needs etc

  • Research prior appraisals to gain understanding of relevant considerations

  • Tailor final deliverables to meet UK HTA needs, via a “hands on” approach, including development of budget impact analysis

  • Write the cost-effectiveness section for submissions to NICE, SMC and AWMSG, working collaboratively with UK Market Access colleagues and Medical team

  • Provide high quality responses to technical assessor questions

  • Represent AstraZeneca to a high standard at appraisal committee meetings

  • Manage the outsourcing of some aspects, as needed

Develop early cost-effectiveness analyses for future brands/indications:

  • Based on target product profile, to inform national market access feasibility assessment, to support internal forecasting process and global-led consultations

  • Research prior appraisals to gain understanding of relevant considerations

Business partnering on priority brands:

  • Develop strong brand and therapy area knowledge to give effective support to Brand Marketing Teams, having taken the time to understand their needs

  • Within cross functional teams, contribute to the strategic and operational planning processes

Essential skills and experience:

  • Postgraduate qualification in health economics

  • Proven experience of developing HE content for HTA submissions in either in a HEOR agency or in the pharmaceutical industry

  • Ability to be able to develop cost-utility analysis and budget impact models in Microsoft Excel

  • Working knowledge (or above) of Microsoft Visual Basic Applications (VBA)

  • Demonstrable record of collaborative working and personal delivery to agreed timelines

  • Ability to be able to prioritise effectively, based on business need

  • Excellent interpersonal and communication skills, including strong written skills

  • Experience of training non-Health Economists in the effective delivery of HE outputs


  • First degree in economics, life sciences, mathematics or similar

  • Experience of managing external suppliers

  • Experience of up-skilling junior HE staff

  • Other experience beyond Health Economics (e.g. NHS)

  • Experience in Cardiovascular, Renal & Metabolic therapy areas

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a phenomenal Place to Work. Where you are empowered to push the boundaries of science and fuel your ambitious spirit. There’s no better place to make a difference to medicine, patients and society. A broad culture that fosters diversity and teamwork, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

If you are inspired by the possibilities of science to make a difference and ready to discover what you can do by joining us on this exciting journey and believe you can contribute to this bold ambition – join us!

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn

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Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

You’ve got this!