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Senior Scientist, In Vivo Pharmacology, Respiratory & Immunology

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time


Perfection not required
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Make a more meaningful impact to patients’ lives around the globe

Here you’ll have the opportunity to make a meaningful difference to patients’ lives. With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines – for the world’s most complex diseases. Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and shaping the patient ecosystem.

We are looking for a Senior Scientist to join our in vivo pharmacology team in Cambridge UK for a fixed term 1 year contract. Respiratory and Immunology is one of AstraZeneca’s main therapeutic areas and our aim is to transform the lives of patients with chronic lung conditions such as asthma and COPD, as well as inflammatory and autoimmune diseases including atopic dermatitis, arthritis and lupus (SLE).

Main Duties and Responsibilities:

We expect you to be a strong in vivo scientist with experience in inflammation biology an outstanding drive for innovation and idea generation. The in vivo team work closely with drug project teams as well as teams identifying new targets to support discovery phase projects and to explore new exciting science.

Accountabilities and responsibilities:

  • Drive science and develop valuable solutions for respiratory and/or inflammatory diseases

  • Responsible for maintaining the highest standards of animal welfare and ethical compliance as well as data integrity

  • In vivo lead for studies supporting pre-clinical discovery and early development projects.

  • Design and develop disease-relevant in vivo models and biomarkers

  • Contribute to the evaluation and interpretation of primary data as well as writing reports and summaries

  • Supporting drug discovery projects to meet their objectives by acting as an effective and creative team member

Essential requirements:

  • PhD in a relevant discipline or MSc complemented with an extensive proven track record of in vivo work

  • Practical In vivo experience and experimental skills in the use of animal models

  • Good understanding of pharmacology, physiology and immunology

  • Analytical skills related to in vivo research and data analysis

  • Good written and oral communication skills in English

  • As highly motivated, independent scientist - be able to work effectively as part of a team and develop ideas by incorporating the views of others

  • Able to communicate effectively across language, cultural, or other barriers

  • Understanding of statistical methods, quality control including data reporting and archiving

Desirable requirements:

  • Respiratory or inflammatory disease knowledge, including target and mechanism knowledge

  • Experience of specialized in vivo techniques and development of in vivo models

Why AstraZeneca?

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or
interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Next Steps – Apply today

Are you already imagining yourself joining us? Good, because we can’t wait to hear from you!

Advertising opens on 13th September 2022 and closes on 27th September 2022

For more information please contact:

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.