Associate Principal Chemoinformatician

AstraZeneca UK

Location: Cheshire East

Job Type: Full time


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Associate Principal Chemoinformatician

Macclesfield or Gothenburg

Salary & Benefits Competitive

Build a long-term career by unlocking opportunities for lifelong learning

Build unrivalled capabilities in a place that promotes learning agility and offers development opportunities. We never stand still so you’ll have the chance to constantly grow your abilities, skills and knowledge. Here we offer a fusion of challenging and interesting work, in an energising and inspiring environment!

Pharmaceutical Sciences is a function within AstraZeneca’s Biopharmaceuticals R&D unit that creates innovative, cost effect solutions by transforming molecules into investigative medicines meeting unmet needs of future patients. The function has five departments: Early Chemical Development, Advanced Drug Delivery, Early Product Development and Manufacturing, Digitisation & Data Science and Modelling. Our wide-ranging portfolio of projects includes traditional small molecules, nucleotide-based therapies and nanomedicines across AstraZeneca’s therapy areas.

The Digitisation department is brand new and passionate about digitally transforming ways of workings: delivering solutions that improve productivity and ensuring the complex experimental data Pharmaceutical Science teams andpartners generate flows seamlessly to be available for data science & modelling.

You'll be a leadmember of this teamdirectly collaborating with a diverse range of world-class scientistsfrom across all our departments. Bringing a passion for working at the interface of science and digital you will be responsible for identifying and developing impactful, innovative & disruptive informatics solutions.

This role could be based at any of our sites with a significant Pharmaceutical Sciences presence: Macclesfield Campus, the Cambridge Hub, or Gothenburg.

What you’ll do

  • Innovate Develop, coordinate implementation and support chemoinformatics solutions to drive the creation & curation of appropriate datasets, facilitate improved science workflows & interrogate those datasets for scientific insight

  • Lead chemoinformatics projects across a range of priority areas including high throughput experimentation (HTE), deployment & utilisation of ELN, drawing tools to support new modalities, integration of external data & tracking & cataloguing of impurities

  • Data stewardship & creation of key reference & master data.

  • Build strong collaboration with both scientists within Pharmaceutical Sciences & the Data Science and Modelling team.

  • Build effective relationships with colleagues across fields in Pharmaceutical Sciences to identify & prioritise opportunities for improved workflow & data transfer solutions.

  • Build strong relationships with an established range of partners across the wider CMC community, IT organisations & the R&D Data office.

  • Develop, maintain and apply ongoing knowledge and awareness in trends, standard methodology and new developments in analytics and data science.

  • Lead digital transformation, agile working practices, FAIR data and the impact of data science.

  • Develop an understanding of the current chemoinformatics ecosystem within AZ and influence of external trends & opportunities.

  • Present or publish work for conferences and in peer reviewed journals.

Essential criteria

  • Bachelor's Degree (or equivalent experience) in mathematics, computer science, chemistry, pharmacy, or material science, or a related subject area.

  • Demonstrated experience of working within a scientific environment but with a passion to develop and learn new informatics skills OR an experienced data / computer scientist with a desire to work in close partnership with lab based scientists.

  • Excellent written and verbal communication, business analysis, and consultancy skills.

  • Basic skills in high level programming or pipelining tools (e.g. Python, Knime, PipelinePilot).

Desirable criteria

  • Masters or PhD degree in mathematics, computer science, chemistry, pharmacy or material science, or a related subject area.

  • Proven track record of publishing relevant results and tools in peer-reviewed journals, conferences, and other scientific proceedings.

  • Good understanding of the design, development, optimization, and scaling of informatics applications and solutions.

Why AstraZeneca

At AstraZeneca we are dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There is no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development.

So, what’s next?

Complete your application before the below closing date!

This role is open from 16/09/2022 andwe welcome your application no later than 30/09/2022

Where can I find out more?

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Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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