Translational Medicine Alliance Manager

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time


About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we are pioneering new frontiers by identifying and treating patients earlier, working towards the aim of eliminating cancer as a cause of death.

We are seeking a talented life sciences professional with a grasp of both technical and strategic skills as well as exceptional communication and organizational skills to join our Translational Medicine team in Cambridge, UK or Barcelona, Spain. You will play a key role in cultivating our relationships with 3rd party innovation partners developing Early Detection and Minimal Residual Disease assays, and supporting our evaluation of these for deployment to our Early Oncology clinical trials as well as providing dedicated Alliance Management support for a key, business critical partnership. The successful candidate would be joining a world class center for discovery and development of innovative cancer medicines.

The scope of the Early Oncology (EO) Translational Medicine (TM) Alliance Management Team is to lead the outsourcing strategy across the EO TM organization; ensure our suppliers deliver to the needs of the organization; and to develop strong, beneficial partnerships with key suppliers.

Come and join our AZ team where you will play a pivotal role in this exciting period of development!!

The role of the Alliance Manager is to handle one or more supplier(s) or outsourcing models within the EO TM team. You will be responsible for ensuring the supplier(s) and / or model(s) are meeting the needs of the Translational Medicine Leads (TMLs) and ensure that selected partners deliver to contract and that strong relationships with the external suppliers are created and maintained ultimately enabling us to access exciting, cutting edge technologies.

We expect you to ensure the maintenance and oversight of supplier / model, ensuring seamless execution, quality and timely delivery of relevant scope of work deliverables and to handle operational governance of the supplier(s) / model(s) and participate in other governance as required. May include co-ordination and / or participation at executive level governance meetings. You will also define and monitor quality and performance of service deliverables in alignment with the project requirements.

Key Responsibilities:

  • The remit of this unique role will allow you to demonstrate leadership on two main high impact projects:

  • Provide Alliance Management support for a key Early Oncology Translational Medicine business critical partnership encompassing, retrospective studies, scientific collaborations and prospective studies with non-registrational intent

  • Work with world-leading external partners to deliver exploratory data on novel assays using contrived and clinical samples. Help build our understanding of the global cancer Early Detection and Minimal Residual Disease technology landscape and deliver our engagement & evaluation strategy with prioritised technology partners. As a key member of our team, you will be responsible for setting the foundation for these key relationships as we kick off pilot studies with a view to forge long-lasting partnerships.

  • Manage day to day interactions with 3rd party partners, including liaison with senior managers, Translational Medicine Leads, TM Operations Leads, TM Leadership Team and project teams both internally and externally to build collaboration and trust

  • Draw up Statements of Work and work-plans to support new biomarker analyses on clinical trial samples

  • Work with commercial partners to plan, procure, deliver and analyse epigenomic data via external labs

  • Maintain oversight of all programs with a partner, and be the “Go to person for the partnership” especially for issue resolution, contracting and governance. This will involve collaborating cross-functionally with Procurement, Business Development, Precision Medicine, etc to establish new relationships/maintain current working relationships, contribute to contracting process to meet project timelines

  • Build and maintain relationships with academic and commercial epigenomics KOL's

  • This is not a lab-based role; rather you will work with 3rd party laboratories who will generate data on their novel technologies using our samples.

  • Alliance Manager is the key point of contact within TM for a dedicated partner and provides agreement templates for TMLs to complete, ensuring consistency in terms and pricing as well as communicating prioritization needs back to the vendor

  • Liaise with Translational Medicine Leads and TM Operations Leads for early stage drug project work and to implement TM biomarker strategy

  • Collect information regarding capabilities, services and upcoming new offerings of new vendors, and form connections and business relationships with new partners to meet our scientific needs


  • University degree in related field, or equivalent

  • Scientific background in the genomics technology space sufficient to allow for technical understanding of service deliverables (e.g. study management, data management, analysis and reporting)

  • Highly motivated with organizational skills demonstrating a strong attention to detail

  • Outstanding verbal and written communication skills

  • Evidence of problem solving, troubleshooting risk management and collaborative working skills

  • Ability to act as an external ambassador and to influence external organizations to enhance the image and reputation of AstraZeneca

  • Demonstrated experience working successfully with external partners

  • Experienced and comfortable working in a matrixed environment

  • Understanding of and adaptable to working variances of different countries and different cultures

  • Strong interpersonal and team player skills, demonstrating flexibility and a proven ability to deal with complexity under time pressure

  • Tenacity and resourcefulness

  • A flexible, team orientated attitude, willing to contribute own skills to deliver AZ priority projects

  • Ability to understand and work to detailed SOPs


  • Scientific background in cancer biology

  • Peer-reviewed publications in the liquid biopsy/cancer biology/cancer genomics field

  • Experience working with DNA/RNA from human clinical materials such as circulating cell-free DNA (cf/ctDNA) or formalin fixed paraffin-embedded tissues

  • Hands-on laboratory experience in genome technologies

  • Conducting work to Good Clinical Practice (GCP) within a regulatory /quality framework (e.g. ISO 15189-, CAP-, CLIA-accredited lab environment).

  • Analysis and interpretation of NGS data

  • Experience in the biotech/pharmaceutical industry and of the drug development process

  • Knowledge of alliance governance frameworks and processes (including performance metrics)

  • Knowledge of partner selection and qualification processes (e.g request for information/proposal, bid defense, operational due diligence)

  • Knowledge of contracting, procurement, and budgeting approval processes

  • Ability to identify continuous improvement & innovation opportunities

  • A high level of cultural sensitivity, interactive communication, negotiation and effective collaboration. This role necessitates considerable tact, discretion and persuasion to obtain desired business outcomes while maintaining ongoing professional relationships

*** We will be reviewing applications and shortlisting on a rolling basis - as such we reserve the right to withdraw this vacancy ahead of the stated closing date

AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next:

Are you already envisioning yourself joining our team? Good, because we can’t wait to hear from you!

Closing date 18th December 2022

Competitive salary and benefits package on offer.

The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, A performance recognition scheme and a competitive, generous remuneration package.

Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

You’ve got this!