Applications for this job have closed. Try searching for similar jobs.

Scientist, Bioscience - Asthma & Skin Immunity

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time


Be empowered to be innovative and creative where difference is valued

Join a place built on innovation and creativity. Where different views and perspectives are welcomed and valued. An environment that champions inclusion, and teams that reflect the diversity of the communities that we serve.

Who we are

A high performing team, we are united and motivated by our shared purpose – to deliver life-changing medicines. We come to work each day to make a difference – to patients, society and our company.

What we do

We are a global, science-led BioPharmaceutical business and our innovative medicines are used by millions of patients worldwide.

Why we love it

This is the place to make an impact. Here we ensure everyone can reach their full potential, perform at their best and make a valued contribution to the enterprise.

Are you a passionate Scientist striving to make a true impact on patients’ lives? The vision of AstraZeneca Early Respiratory & Immunology is centred on delivering life-changing therapies that advance world health and help fight and cure disease. Here, you’ll have the opportunity to make a difference in people’s lives every day. Are you ready to join us and see what science can do?

At AstraZeneca, we believe in the potential of our people and you’ll develop beyond what you thought possible. We make the most of your skills and passion by actively supporting you to see what you can achieve no matter where you start with us.

We are seeking a highly motivated Scientist researcher to join the Bioscience Asthma & Skin Immunity research group in Cambridge, UK to work on an independent research project focused on investigating the pathogenesis of lung and skin diseases and the identification of novel targets. Within our Cambridge based research team, we are seeking an experienced research scientist with a strong understanding of screening and experience with mammalian cell culture. In this role, you would be expected to demonstrate an exceptionally high level of enthusiasm for innovative scientific research leading to the discovery and development of novel therapeutics. Ideally, you have some expertise in immunology, and an ability to apply this experience to an understanding of the basic mechanisms of human lung and skin pathologies.

What you’ll do:

This job is a lab-based research role, and you will have a significant opportunity to contribute to the developments of new therapies in the Bioscience Asthma & Skin Immunity research group in Cambridge, UK. The work will be predominantly focused on screening of candidate drug molecules in disease-relevant in vitro assays. This work will involve culture of cell lines as well as primary immune cells.

  • The role will be based in Cambridge within AstraZeneca’s state-of-the-art laboratories where you will follow the science to help drive innovation and advance medicine to help improve patient lives.

  • You will collaborate with scientists from a variety of functional teams in Cambridge and with our sites in Gaithersburg, US and Gothenburg, Sweden.

  • You will benefit from daily interaction and collaboration with highly accomplished scientists and the position offers a unique opportunity to work in a dynamic and innovative environment developing your career at the interface of research and drug discovery.

  • Encouragement and support will be provided to help you develop specialist knowledge and skillsets.

Key Responsibilities and Accountabilities:

  • We are looking for a motivated new member of the team, able to learn and grow in our organisation. The successful candidate will provide broad laboratory-based support to our ongoing lung and skin biology projects.

  • A team player able to collaborate on multiple projects

  • Work under manager’s supervision to carry out key lab tasks

  • Accurately record and assess all data generated in course of analyses with a high attention to detail

  • Solve technical and logistical challenges

  • Ensures that work is performed in accordance with appropriate Safety, Health & Environment (SHE), quality and compliance standards

  • Excellent communication with manager and team

Education, Skills and Qualifications:

  • A minimum of 5 years relevant laboratory experience with a BSc, MSc, PhD (or equivalent) in Biochemistry, Cell Biology, Molecular Biology, Immunology or a related field in Biological Science

  • Work experience in Pharma/Biotech industry is desirable

Required Skills:

  • Strong hands-on experience with cell/tissue culture, and ideally experience with the culture of human primary cells.

  • Ability to evaluate cellular responses by various means, for example flow cytometry, ELISA, Western blotting, PCR, imaging, try and/or other similar technologies

  • Highly organised and self-motivated, with the ability to work independently as well as collaboratively within a team to conduct a high-level research project.

  • Ability to critically analyse data sets

  • Demonstrated ability to function as part of a team and run collaborative efforts

Desired Skills:

  • Experience with one of the following areas would be advantageous but is not a requirement

  • Experience of multiparameter FACS analysis is highly desirable

  • Experience in drug discovery projects and screening compounds in immunology or a closely related field of biology

  • Experience in management, recording and processing of human samples

  • The ability to develop in vitro and ex vivo models to understand mechanisms important in disease

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

So, what’s next?

Are you already imagining yourself joining us? Good, because we can’t wait to hear from you!

Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.