Associate Principle Scientist Cell Immunology - Adenovirus

Full time
employer logo
AstraZeneca UK
Healthcare & medical
10,001+ employees
Compare top employers
Apply on company site

Associate Principle Scientist Cell Immunology - Adenovirus

Location: Cambridge, UK

Competitive salary & Benefits

Introduction to role:
Are you ready to make a significant impact in the field of gene editing and immune cell enhancement? We are seeking an Associate Principal Scientist to join our Cell Immunology team within the Cell, Gene and RNA Therapies department of Discovery Sciences. This lab-based role will focus on developing novel high capacity viral vector technologies based on Adenovirus. You will be at the forefront of crafting and driving the strategic direction for gene delivery via Adenovirus to enable AZ’s portfolio of cell therapies to advance to the Clinic.

As an Associate Principal Scientist, you will be responsible for the development of scientific research strategies related to viral vector development and gene delivery methods. You will set strategic direction to ensure that the scientific priorities are aligned to business needs and act as the internal expert in this field. You will initiate and manage internal and external research investigations, collaborations, and partnerships in line with agreed business needs. You will also play a key role in the scientific development of staff, ensuring that the capability maintains a leading edge and keeps pace with the needs of the business.

Essential Skills/Experience:

  • Ph.D. or equivalent experience in virology, immunology, cell biology or molecular biology
  • Strong working knowledge of Adenovirus biology
  • Experience with viral vector engineering, pioneering cloning methods, cassette optimisation, and multi-gene expression construct development
  • Expert in viral packaging and manufacturing including Adenovirus, Adeno-Associated virus, and Lentivirus
  • Experience with mammalian cell culture (stable and adherent lines), genetic engineering (e.g. CRISPR), and molecular and cell biology techniques such PCR and RT-PCR, FACS, flow cytometry, FACS, transfection, transduction, and assay development
  • Experience of working in external collaborations both in academia and pharmaceutical industry
  • Track record in scientific excellence as demonstrated by prior project/technology development success and publication history
  • Experience with mentoring, supervising, coaching junior staff

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference by fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. We are always listening and learning from people who live with the diseases our medicines treat. It enables us to better understand their needs and, ultimately, diagnose and design the right treatments to impact patients' lives.

Are you ready to be part of a team that makes a bigger impact on patients' lives? If your passion is science and you want to be part of a team that follows the science unlike anywhere else, then there's no better place to be. Apply today!

So, what’s next?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!

To be considered for this exciting opportunity, please complete the full application at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.

Welcome with your application no later than 21/07/2024

Where can I find out more?

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Date Posted


Closing Date

21-Jul-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.