Senior Scientist Cell Biology & Immunology - SRS complex vector engineering

Full time
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AstraZeneca UK
Healthcare & medical
10,001+ employees
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Senior Scientist Cell Biology & Immunology - SRS complex vector engineering


Competitive Salary & benefits package

Introduction to role:
Are you ready to embrace new and varied opportunities to develop and learn? We are seeking a Senior Scientist to provide technical and hands-on expertise on complex molecular biology, high throughput cloning, cassette and multigene expression construct optimisation. This role is crucial in supporting immune editing cell therapy discovery, technology development projects and helping build the next generation manufacture strategies to drive our Cell Therapy ambitions.

As a Senior Scientist, you will independently design, plan and implement engineering and screening strategies for Immune Cell Therapy discovery or technology projects. You will work as part of multi-disciplinary research drug discovery/technology project teams, contributing to the development of clinical manufacture strategies, reagents or targets to support cell therapy discovery projects. You will record and interpret complex experimental results, analyse and report findings to manager, project teams and the wider organisation. You will also provide training/guidance to junior scientists on technical and functional processes.

Essential Skills/Experience:

  • PhD or equivalent experience in Molecular Biology, Cell Biology or Immunology
  • Extensive experience with complex vector engineering, high throughput cloning (e.g. Golden Gate cloning), cassette optimisation, multigene expression screening.
  • Experience with mammalian cell culture (stable and adherent lines), vector engineering, molecular and cell biology techniques e.g. PCR, FACS, flow cytometry, FACS, transfection, transduction, and assay development.
  • Experience with gene editing technologies. (CRISPR/Cas9, TALENs, Zinc Finger nucleases)
  • Scientific excellence as shown by previous work and publication history.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. In this lab based role you will work on average, five days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference. We have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

Are you ready to join a team that's unlocking the power of what science can do? Are you ready to push the boundaries of science to deliver life-changing medicines? If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be.

Take the next step in your career and apply today!

We encourage your application (including CV and cover letter), no later than 21st July 2024.

Where can I find out more?

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Date Posted


Closing Date

21-Jul-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.