Position: Senior Director Project Toxicologist - Clinical Pharmacology and Safety Sciences

Location: Cambridge, UK

Competitive Salary & Excellent Company Benefits

Applications Closing Date: 9th October 2026

Are you passionate about working for a global health care company who truly puts patients first, and would like to apply your toxicology expertise in a company that is accelerating innovative science and turns ideas into life changing medicines?

AstraZeneca discovers and develops medicines in our core areas of Oncology, Respiratory and Immunology, Microbial Sciences and Cardiovascular, Renal and Metabolic Disease.

We are looking to recruit a talented Senior Project Toxicologist who has prior experience of late stage clinical development and global marketing into our Regulatory Toxicology and Safety Pharmacology team. In this role you will work as a Project Toxicologist on compounds in late clinical development and marketed products in multiple therapy areas. In collaboration with colleagues across our R&D organization you will develop and execute global regulatory toxicology strategies, playing a key role in delivering new medicines to market. As a Senior Project Toxicologist you will use your prior experience of successful marketing to coach others through the marketing and regulatory defence process. The role will be based at our vibrant R&D sites The Discovery Centre, Cambridge UK.

Job responsibilities include:

• As a core member of the project team, you will design regulatory toxicology strategies to assess and mitigate safety risks, delivering projects to successful global marketing. Provision of non-clinical safety expertise to support established brands.
• Communicate clear positions on integrated risk assessments including informing decision-making governance bodies and author/defend clinical trial and marketing applications.
• Coach others through the process of global marketing applications and regulatory defence
• Maintain expertise in regulatory requirements and preclinical safety approaches.
• Conduct specialist non-clinical safety evaluation of in-licensing opportunities.

Education/Experience Requirements

• Excellent scientist with a PhD and/or DABT in Biology, Toxicology, Pharmacology or related field, a strong scientific track record, and a willingness to challenge conventional thinking.
• Extensive experience working as a Project Toxicologist across different therapy areas within the pharmaceutical/biotech project environment delivering pre-clinical toxicology packages and successful marketing for a range of modalities which should include small molecules, peptides and oligonucleotides.
• A collaborative, team-oriented approach, able to solve problems in a goal-focused fashion with capacity to coordinate tasks across multiple projects. A proven track record as a successful coach/mentor of others.
• Excellent communication, presentation, interpersonal and influencing skills across levels/subject areas with a strong desire to drive personal development.
• Experience and desire to work with teams across geographies including awareness of inclusion and diversity. Adopting a working style that is inclusive and collegiate, contributing to our Great Place to Work objectives.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn't mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Ready to make a difference? Apply now!

Date Posted

Closing Date