Senior Data Scientist

AstraZeneca UK

Location: Cambridgeshire, Gaithersburg, Maryland

Job Type: Full time

Posted

Be brave, not perfect.
- Reshma Saujani

Senior Data Scientist

Barcelona (ESP), Toronto (CAN), Gothenburg (SWE), Cambridge (UK), Gaithersburg (US),

Competitive Salary + Benefits

Make a more meaningful impact to patients’ lives around the globe

Here you’ll have the opportunity to make a meaningful difference to patients’ lives. With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines – for the world’s most complex diseases. Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and shaping the patient ecosystem. With our ground-breaking pipeline, the outlook is bright. Be proud to be part of a place that has achieved so much, yet is still moving forward. There’s no better time to join our global, growing enterprise as we lead the way for healthcare and society

The Center For Artificial Intelligence (CAI) is a lab focused on applying machine learning research to the toughest challenges at AstraZeneca. We are a team of experts from different disciplines including Machine Intelligence, Data Science, Real World Evidence and Bioinformatics.

We innovate together with our leading biologists, chemists, and clinicians to close the gap between today's challenges and the forefront of machine learning. If you want to have an impact on transforming patients' lives by accelerating new medicines to patients, this may be the position for you!

We are looking for a Senior Scientist, Data Scientist to join our Data Science team.

What you’ll do

In this role, you will work directly with our stakeholders across BioPharma R&D (which includes respiratory, immunology, cardiovascular, renal, metabolic, neuroscience and vaccines) to deliver insights from clinical data, and work collaboratively with other teams within the Centre for Artificial Intelligence to deliver innovative machine learning solutions.

Your work will have a significant impact by accelerating the delivery of drugs to our patients. You will work on challenges such as identifying sub-groups of patients from biomarker data, integrating external data to supplement interpretation, and leveraging innovative methodologies for interpreting clinical trial data. Your work will support activities across early and late stages of clinical development.

You will have the opportunity to collaborate extensively with other teams across the organization, with the goal of delivering products and novel insights.

This role is critical in applying research from our teams in knowledge graphs, computer vision, audio processing, big data, target identification, -omics technologies, scientific portfolio knowledge management, predictive science, precision healthcare and patient information into the challenges faced by biopharmaceutical R&D. It is expected you will present your findings to clinical and senior stakeholders and publish your findings in scientific journals and conferences.

Key responsibilities

  • Exploratory Data Analysis of clinical data using data science, machine learning and visualisation to support design and interpretation of clinical trials

  • Contribute to and apply machine learning research to challenges faced by the therapeutic areas.

  • Communicate machine learning and statistical methods and insights to various domain experts, eg: clinical teams, data scientists, senior management, statisticians, external collaborators

  • Contribute ideas and provide creative input to clinical research teams

  • Work efficiently as an individual or in a team of 3-10 to optimally deliver projects across AZ business areas

  • Work to GxP standards required for clinical trial analysis

  • Continue to develop as a data scientist, through attendance at conferences and personal development (10% allocated time)

Examples of projects this team works on include:

  • Inform clinical study design through machine learning led selection of subjects who are most likely to respond to treatment (eg: super-responders) or to experience a clinical event (eg: fast progressors)

  • Mining real world data to identify covariates of clinical risk

  • Model and simulate treatment response in clinical trial data to rank covariates of clinical response

  • Deploy novel data science methods for analyzing clinical trial data to support clinical development and regulatory submissions

    • Patient risk models

    • Counter-factual event models

    • Biomarker driven efficacy models

Essential for the role

  • B.Sc. degree in data science, computer science, life sciences, statistics or related field

  • Advanced degree (M.Sc/Ph.D. or equivalent experience) in machine learning, data science, computer science, statistics, life sciences or related field

  • 3+ years' experience as a data scientist / machine learning scientist

  • Experienced in Python

  • Track record of collaborating successfully with stakeholders and delivery of impactful datascience projects and analyses

  • Familiar with modern software engineering practices and the use of modern collaborative tools (e.g. AWS or similar, GitHub, Jira, unit testing etc.)

Desirable for the role

  • Ph.D. or equivalent experience in machine learning, data science, computer science, statistics, life sciences or related field.

  • Experience within the pharmaceutical industry and ability to demonstrate understanding of drug development and clinical trial process and data (all phases)

  • Experienced with clinical data standards, medical terminologies and controlled vocabularies used in healthcare data and ontologies

  • Use of Machine Learning and Artificial Intelligence in the generation of hypotheses from patient level data

Why AstraZeneca?

At AstraZeneca we’re dedicated to being an excellent Place to Work. Where you are empowered to push the boundaries of science and unleash your ambitious spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

  • Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.
  • Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

#DataAI

#DSAI

Date Posted

15-Sep-2022

Closing Date

27-Oct-2022

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

You’ve got this!