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Statistical Science Associate Director – Early Respiratory & Immunology Statistics, BioPharmaceuticals Biometrics

AstraZeneca UK

Location: Cheshire East, Durham, North Carolina, Gaithersburg, Maryland, Waltham, Massachusetts, Wilmington, Delaware

Job Type: Full time


Are you passionate about statistics, confident to lead and collaborate with a curious mind? Are you keen to shape the future of statistics, transform the way we work with clinical trial design to build the basis for drug development? Then join the team unlocking the power of what science can do. Welcome to AstraZeneca!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide, while applying groundbreaking approaches to science across many business areas. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to act, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

We are recruiting a Statistical Science Associate Director or Statistical Science Director to join our growing Early Respiratory & Immunology statistics team to support the Early Phase Respiratory & Immunology/Neurosciences/Vaccines & Infections portfolio. Our main focus is providing statistical project lead support for all of Early phase of clinical development for AZ’s Respiratory & Immunology, Neuroscience and Vaccines & Infections division together with specific targeted support for the development and innovation of Early Phase Biopharmaceutical trials.

In this role, you will belong to the Early Biometrics & Statistical Innovation (EB&SI) department, where our data-centric focus helps us work efficiently and creatively to bring the right medicines to the right patients. Our teams use their expertise in statistics and programming to address drug development objectives and reduce uncertainty in product development, driving better business decisions with quantitative reasoning. As part of the Data Science & AI team, you’ll use technology at the forefront of science in a creative environment, with the scope to develop new statistical ideas and apply them in your work.

Main duties and responsibilities

In this role you’ll lead the delivery and oversight on multiple studies/indications within multiple drug projects as a Global Project Statistician. You will work closely with the full team providing targeted statistical support to the Therapy Areas. You’ll participate in adapting and developing statistical methodology and participate in innovation workstreams facilitating innovation, improvement and development of how we do Early Phase Clinical trials.

With your unique skills you’ll contribute to the basis for innovative drug development. Working cross-functionally and within an international environment you’ll lead the statistical thinking and contribute to the delivery of early development studies, development plans, regulatory strategy, health technology assessment and commercial evaluation. As a subject matter expert and with excellent project management skills you’ll guide statistical staff and/or CRO partners, to ensure delivery to standards, quality and time. Additionally, you’ll mentor and support the education of early statistical talent.



  • The minimum required education is a M.Sc./PhD degree in a relevant discipline such as statistics, biostatistics, or mathematical statistics
  • Experience in the relevant therapeutic areas
  • Strong knowledge of programming in R and/or SAS
  • Understanding of the technical and regulatory requirements related to the role
  • Excellent communication skills and desire to build strong collaborative relationships
  • Desire to apply your scientific competence on practical problems, for the benefit of patients


  • Knowledge / research experience in the development of statistical methodology related to vaccines & infections, analysis and interpretation of safety data, observational studies, meta-analysis, Bayesian statistics, non-linear and mixed effect models.
  • Broad awareness of statistical issues against the evolving scientific and regulatory landscape

Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.