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Research Scientist – Protein Scientist, Biologics Engineering

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time


We are looking for an expert in the field of molecular biology, to carry our protein expression and protein purification independently and unsupervised to enable delivery of target proteins to support our biotherapeutics portfolio. In this role you will employ experimental strategies to deliver project milestones and technology advancements.

About AstraZeneca

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Site description

Granta Park, Cambridge (UK), is one of over 400 sites here at AstraZeneca, providing an environment where everyone feels comfortable and able to be themselves is at the core of AstraZeneca’s priorities, it’s important to us that you bring your full self to work every day. To help you maintain your best self, here’s a sneak peek into some of the things this site provides for you…Cambridge is one of the most exciting bioscience hotspots in the world and plays a central role in our mission to deliver life-changing medicines to patients. Granta Park has a gym, nursery and central restaurant/coffee place as part of the science park facilities that are accessible to our staff. We also have our own bistro and deli in the AZ buildings. There are regular lunch & learn events including running clubs and after work socials on the last Friday of every month.

Business area

Biologics Engineering is responsible for the discovery and optimisation of biologics candidate drugs across all AZ therapy areas such as oncology, respiratory and inflammation, cardiovascular, renal and metabolic diseases. We are constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for the development of in-house biologics discovery platforms and novel drug modalities to address unmet medical needs.

What you’ll do

  • Design molecular biology, protein expression and purification strategies to provide key proteins to enable therapeutic biologics drugs projects

  • Apply expertise in molecular biology, protein expression and purification to facilitate the development of next generation biologics

  • Make detailed observations, analyses data, interpret results and devise solutions to complex scientific problems

  • Maintain and develop knowledge of protein expression and purification capabilities

  • Make decisions on protein supply strategies based on their own findings, the findings of others, and factors from outside the company

  • Provide support and delivery to projects through matrix working and collaboration

  • Experienced specialist in their area of expertise. Establish internal networks and collaborations within scientific field of value to the business and presents data at internal (intra- and inter-departmental) meetings

  • Demonstrate strong interpersonal communication by establishing good working relationships with team and department members and others within the company

Essential for the role

  • BSc/higher degree with extensive lab-based experience

  • In depth knowledge and strong technical skills in molecular biology, protein expression technologies (in particular mammalian expression systems) and protein purification

  • Extensive experience in leading and troubleshooting recombinant protein delivery

  • A history of successful project delivery

  • Excellent communication, capable of developing good working relationships with individuals and experience working within a team environment

Desirable for the role

  • Background in drug discovery and development in the pharmaceutical industry

  • Experience with stable cell line generation to express recombinant proteins

Why AstraZeneca?

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. A culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

  • Are you already considering joining the team? Good, because we can’t wait to hear from you.

  • Are you ready to bring ideas and fresh thinking to the table? Brilliant! We have one seat available, and we hope it’s yours.

  • If you’re curious to know more please get in touch with Louise Bennett

Competitive salary package and benefits

Close Date: 13/12/2022

Where can I find out more?

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Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.