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Lead Project Manager, Oncology R&D

AstraZeneca UK

Location: Cambridgeshire, Gaithersburg, Maryland

Job Type: Full time


We are looking for curious, proactive and highly collaborative Project Leads with a robust understanding and experience of the drug development lifecycle to support strategic programmes that will help fundamentally change the way we work and operate to help Oncology R&D meet its bold ambition.

You will sit in the PMO in the Oncology Chief Operating Office and support Oncology on critical strategic priorities that often span multiple SET areas. You will work with senior stakeholders up to SET-1 level on a wide range of programmes and gain exposure to different processes and functions.

You will be able to motivate others, take ownership for projects and maintain high standards for delivery. You will work within programme / transformation teams and the business to ensure deliverables fall within scope and budget and coordinate with other departments and / or Project Managers to ensure alignment between different initiatives.


  • Manage complex programme(s) within the portfolio supporting a Programme Lead who has overall accountability for the portfolio of projects and programmes

  • Define the roadmap and agree the programme scope and boundaries

  • Agree and deliver plans for projects / programmes (or contribution in part to a larger project) including activities, resources, costs, roles, responsibilities and quality

  • Manage programme budgets, forecasts, tasks, schedules, risks, change management, and status to support effective decisions and project reporting to stakeholders and review boards. Coordinate status and delivery of project workstreams. Identify / manage dependencies between projects (intra-program and across portfolio).

  • Assure / develop transition plans to ensure project delivered solutions are sustainable within a BAU operations environment, including controlled hand-over into operational support.

  • Manage relationships with key business stakeholders to ensure the effective capturing of business requirements and commitment to project/program objectives. Responsible for steering / stakeholder meetings, communication of status, issues, risks.

  • Ensure effective risks & issues management processes are in place and effectively used. Resolve problems and escalate as appropriate.

  • Build a cohesive project team and provide the leadership necessary to maximize the team’s success. Provide individual coaching and development of team members as needed.

  • Manage changes to project/programme scope, ensuring that all impacts and changes are approved and appropriately communicated to stakeholders and review boards.

  • Develop service transition plans including controlled hand-over into support and maintenance.

  • Ensure the project team adheres to all PMO standards, processes, capabilities, and best practices.

  • Establish project governance and lead project governance meetings as required

  • Ensure expected benefits realization is consistent with project deliverables and clearly understood by stakeholders and project team.

  • Support continued development of a world-class centre of excellence for project management capabilities and ensure that best practice is adopted and reinforced.

Essential Skills

  • Robust and in depth knowledge and experience of drug development

  • Very strong stakeholder management skills

  • Ability to identify and maintain tight control over all aspects of the programme

  • Experience leading and developing project teams with a diverse blend of skills and capabilities

  • Evidence of shaping innovative solutions that have a major impact within the business area and organisation

  • Proven problem solving capabilities.

  • A capable knowledge of Financial Management and Benefits Delivery practices.

  • Strong communication, relationship and consulting skills

  • Excellent business acumen with sensitivity to environment

  • Experience with project management and delivery methodologies and standards

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering innovative methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what’s next?

A place built on courage, curiosity and collaboration – we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take calculated risks that write the next chapter for our pipeline. If you are inspired by the possibilities, don’t hesitate in submitting an application today!

Where can I find out more?

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.