At AstraZeneca, innovation is more than just research. As one of the world's leading pharmaceutical companies, we’re passionate about providing innovative, effective medicines that make a real difference in important areas of healthcare. We’re investing in a state-of-the-art research centre and corporate headquarters at the Cambridge Biomedical Campus, and we seek to bring together the finest talent in business and academia. Join us, and you’ll be part of a brand-new vision for a critical industry, making an outstanding difference world-wide.

As part of this exciting journey we are seeking a hardworking chemist to join us in Cambridge on a permanent basis, with an outstanding team who are working to discover, develop and deliver the right drugs to the right people, in order to make a life changing difference to patient survival.

You will help us explore the amazing things which science can do, working on projects from lead optimisation through to candidate selection. As part of the Medicinal Chemistry Discovery Process group you will be responsible for implementing strategies and leading outsourcing campaigns to deliver multi-hundred gram quantities of intermediates and Active Pharmaceutical Ingredients, conceiving and implementing innovative synthetic solutions to deliver the next generation of Oncology medicines.

Essential requirements

• A degree or Ph.D. in a chemistry-related discipline.

• An ability to lead technically complex outsourcing campaigns to deliver multi-hundred gram quantities of intermediates and Active Pharmaceutical Ingredients for early phase projects at the Discovery/Process interface. A proven track record of delivering innovative solutions to complex problems within agreed timelines.

• Experience with working with external partners

• Excellent team-working and communication skills; an ability to constructively challenge assumptions and strongly influence the strategy of cross-disciplinary project teams.

• A strong background in synthetic organic chemistry with an appreciation for the phase-appropriate route development work required to enable early scale-up campaigns.

• Clear understanding of contemporary synthetic organic chemistry.

• A keen eye for detail.

• Good experience of multi-tasking across multiple activities simultaneously

Desirable requirements

• Experience of working at the interface of Medicinal Chemistry and Process Chemistry.

• Experience of transfer of laboratory processes to larger scale (e.g. Kilogram-Lab).

• Awareness of contemporary drug design principles and how modern synthetic technologies such as high throughput experimentation, flow chemistry and biocatalysis can be used in the drug discovery process.

• Experience of coordinating diverse collaboration models (FTE and fee for service)

Why AstraZeneca?

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

• If you are already imagining yourself joining our team, good, because we can’t wait to hear from you!

Competitive salary and benefits package on offer.

The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, A performance recognition scheme and a competitive, generous remuneration package.

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.