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Synthetic Chemist

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time


At AstraZeneca, innovation is more than just research. As one of the world's leading pharmaceutical companies, we’re passionate about providing innovative, effective medicines that make a real difference in important areas of healthcare. We’re investing in a state-of-the-art research centre and corporate headquarters at the Cambridge Biomedical Campus, and we seek to bring together the finest talent in business and academia. Join us, and you’ll be part of a brand-new vision for a critical industry, making an outstanding difference world-wide.

As part of this exciting journey we are seeking a hardworking chemist to join us in Cambridge on a permanent basis, with an outstanding team who are working to discover, develop and deliver the right drugs to the right people, in order to make a life changing difference to patient survival.

You will help us explore the amazing things which science can do, working on projects from lead optimisation through to candidate selection. As part of the Medicinal Chemistry Discovery Process group you will be responsible for conceiving and implementing innovative synthetic strategies while using your personal lab delivery expertise to help solve complex chemistry problems to deliver the next generation of Oncology medicines.

Essential requirements

  • A degree or Ph.D. in a chemistry-related discipline.

  • Practical experience of scale up and route development to deliver multi gram quantities of intermediates and Active Pharmaceutical Ingredients.

  • Expert knowledge of contemporary synthetic organic chemistry and ability to deliver innovative solutions to projects

  • Propose experimental strategies, troubleshoot laboratory-based problems and make a positive contribution to the practical delivery to drive project progress

  • Effective levels of communication and scientific drive.

  • Excellent team-working skills and ability to deliver to agreed timelines

  • A detailed understanding of the chemical sciences and how they influence drug discovery and the ability to represent chemistry in a cross-disciplinary project team.

  • Maintain access to the best internal & external science.

Desirable requirements

  • Experience of working with external partners.

  • Experience working at the interface between Medicinal Chemistry and Process Chemistry

Location: Cambridge UK

Why AstraZeneca?

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

  • If you are already imagining yourself joining our team, good, because we can’t wait to hear from you!

Competitive salary and benefits package on offer.

The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, A performance recognition scheme and a competitive, generous remuneration package.

Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.