Global Procurement Manager- External Manufacturing, Large Molecule

AstraZeneca UK

Location: Cheshire East, Gaithersburg, Maryland

Job Type: Full time


AstraZeneca is on a path to deliver at least fifteen new medicines before the end of the decade.

As a global business, we are playing our part in solving the biggest challenges of our time, from climate change to access to healthcare and disease prevention. We are harnessing the power of science and innovation and our global reach to make a positive impact on society, healthcare systems, and the environment. This starts with us, but matters to everyone, everywhere.

Committed to science-led innovation, our investment in new technologies is providing ground-breaking next generation therapies such as CAR-T, TReg Stabilisation, in vivo expressed biologics, protein therapeutics, ADCs and mRNAs. Operations Procurement is at the forefront of establishing external manufacturing partners for these new technologies emerging in the AZ early pipeline.

The role

Reporting to the Associate Director of Clinical External Manufacturing Procurement, the OPM role is key to crafting AstraZeneca’s supplier landscape to support our emerging pipeline of large molecules through manufacturing of Drug Substance (DS), Active Pharmaceutical Ingredients (API) & Drug Product (DP) for Phase 1-3 supply. You will be at the forefront of establishing external partners through market analysis and sourcing projects, collaborating closely with business partners in Biopharmaceutical Development (BPD) & Global Technical Operations (GTO). You will supply to overall API and Formulation & Packing Category Strategies, working closely with Therapy Area Leads and Global Category Managers in the Commercial External Manufacturing Procurement team to connect clinical and commercial Sourcing strategies.

What you’ll do


  • A key member & contributor of the Clinical Large Molecule Procurement Boards (Drug Substance & Drug Product)
  • Lead core category meetings with business partners, crafting an evolving supplier landscape
  • Ability to connect clinical & commercial strategies both within team and across partner groups.
  • May lead improvement initiatives & workstreams to support wider team & delivery of procurement objectives
  • Negotiating sophisticated supply agreements

Business & Supplier Engagement:

  • Working closely with colleagues in Global Procurement Services, Poland to initiate source to contract activities
  • Developing excellent relationships & influence with internal customers
  • Develop positive relationships with vendors to achieve driven value and quality of services
  • Delivering on AZ Procurement Value Proposition
  • Leads and monitors supplier spend & records savings.
  • Ensuring procurement processes and supplier management are applied in line with
  • Identified AstraZeneca standard operating policies, compliance, ethics & procedures.
  • Handles the business relationship with key suppliers, on behalf of employees and the business, coordinating and running the procurement process and customer happiness
  • Collaborating with the business collaborators to deliver RFPs and Statement of Works.
  • Develops and nurtures technical expertise and knowledge within project team or broader
  • Procurement function by disseminating standard methodologies and sharing knowledge across functions and project teams
  • Support AZ’s industry-leading Sustainability agenda with suppliers

Required skills

  • Degree level or equivalent qualifications
  • Excellent solid understanding of the pharmaceutical industry
  • Knowledge of new biotechnology platforms.
  • Minimum 7 years in Procurement / Business Development roles
  • Minimum 5 years in similar roles in Bio Tech or Pharma
  • Project & time management
  • Supplier relationship management, negotiation & influencing.
  • Technical expertise in at least one Procurement area, and competence in several others
  • Communication skills and ability to influence others
  • Excellent collaborator
  • Partner Management
  • Comfort with risk and ambiguous situations

Desirable skills

  • Life science degree
  • Sustainability platform requirements of CDMOs
  • Digital Management & System Usage
  • Use of collaboration platforms like Sharepoint, Box etc

Date Posted


Closing Date

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

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