Senior Scientist - Upstream Bioprocess Development

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time


Bold disruptors. Push the boundaries of science. Fearlessly break new ground

Work at the cutting-edge, where scientific innovations and an entrepreneurial spirit are the norm.

Cambridge, UK

Competitive salary and benefits

Bold disruptors. Push the boundaries of science. Fearlessly break new ground

Work at the cutting-edge, where scientific innovations and an entrepreneurial spirit are the norm.

In return, you'll be welcomed into a state-of-the-art facility with opportunities to work on one of the most exciting biopharmaceutical pipelines in the world. The range of therapies is diversifying into bispecific protein molecules, RNA therapies, ADC and viral vectors. There are opportunities to innovate in process development with culture intensification, perfusion processes, PAT implementation and automation.

We also have exciting and fruitful academic collaborations for fundamental understanding of the science underlying bioprocessing. We're looking for curious minds, comfortable taking smart risks, always learning, growing and striving for success.

With deep roots and a proud heritage, AstraZeneca UK is a well-known brand and respected company, with a strong reputation in both the scientific community and academia.

Our belief powers us to push the boundaries. We keep moving forward, celebrating successes along the way.

What you'll do

  • Applies technical knowledge and expertise to achieve project targets in a timely fashion and to agreed quality standards to help advance the most exciting pipeline in the industry
  • Independently, assesses and reports data with a clear understanding of its reliability, interprets findings and draws authoritative conclusions and recommendations so that their significance can be appreciated.
  • Provides training /guidance to junior scientists on technical and functional processes.
  • Helps to develop new and innovative techniques and methodologies and draws up relevant investigations.
  • Liaises with colleagues from other fields with the purpose of discussing project-related matters, sharing experiences and reporting progress.
  • Contributes to the management of external collaborations, e.g. consultants and contract research organisations.
  • Uses own knowledge and expertise to input into management decisions about channelling resources to reduce risk associated with inappropriate investment decisions.
  • Develops own level of scientific competence by keeping abreast of relevant scientific developments, by collaborating with peer scientists or through contacts with external groups.

Essential criteria

  • PhD or bachelors/masters degree with equivalent and proven experience within the field.
  • Experience in the biopharmaceutical industry especially in upstream bioprocessing.
  • Understanding of principles and concepts in upstream bioprocessing.
  • Direct experience of bioreactor systems for the cultivation of mammalian cells (including Ambr 15, Ambr250 and bench scale systems).
  • Understanding of regulations and relevant compliance systems in upstream bioprocessing.
  • General understanding of other Discovery / R&D subject areas and their role in achieving the objectives of research area.

Desirable criteria

  • Interest and experience of cell culture automation and process integration.
  • Exposure to PAT technologies for process monitoring and control.
  • Technical excellence with demonstrable troubleshooting and problem solving ability.
  • Continuous bioprocessing expertise.

Why AstraZeneca

At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

So, what's next?

Complete your application before the below closing date.

This role is open from 13th March 2023 to 27th March 2023

Where can I find out more?

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