Head of Global Respiratory & Immunology, Clinical Pharmacology & Pharmacometrics

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time


Are you an experienced, scientific leader looking for a hybrid role in clinical pharmacology and pharmacometrics? Do you also possess great experience with respiratory and immunology development (P1-PIV)? If yes, this might be you next role!

We are looking for a Head of Global Respiratory & Immunology, Clinical Pharmacology & Pharmacometrics to join our Clinical Pharmacology & Quantitative Pharmacology (CPQP) department and lead a global team supporting R&I Portfolio. In this role you will be placed on our vibrant R&D site in Gothenburg, Sweden or Cambridge, UK.

CPQP is part of the broader organisation Clinical Pharmacology & Safety Sciences (CPSS), where we are involved from early discovery through to launch and commercialization of drug candidates and approved drugs. We’re spread across five sites and are tasked with finding the right dose for the right patients using a deep understanding of pharmacology, combined with advanced quantitative methods including statistical and mechanistic mathematical models.

This is the place to go beyond discovery – we think holistically about patients and are always learning from those living with diseases.

What you will do:
The Head of Global Respiratory & Immunology (R&I), Clinical Pharmacology & Pharmacometrics will be accountable for delivering the early and late R&I portfolio. You are an excellent people leader and line manager of Clinical Pharmacology Scientists and Pharmacometricians. You also have significant expertise in respiratory and/or immunological diseases & drug development, diverse drug modality experience including small molecules, monoclonal antibodies and novel modalities. In this role you will be accountable for driving scientific innovation within your team across the drug development phases (1-IV). You will be a member of the CPQP leadership team and support the head of CPQP in functional management and strategic initiatives.

Responsibilities include:

  • Delivering on all new modalities in R&I TA, including supporting R&I filings across different modalities.
  • Leading and developing a global, excellent team supporting the R&I Portfolio.
  • Accountable for the review/approval of clinical pharmacology/pharmacometric elements for regulatory submissions (eg. IND, EoPh II, BLA/NDA documents and meetings).
  • Representing Clinical Pharmacology in discussions with key R&I stakeholders and other departments and ensuring close collaboration with partner functions.
  • Championing diversity, inclusion and a culture of lifelong learning.

Essential in the role:

  • PhD/MD degree with a focus on Clinical Pharmacology, Pharmacometrics, Pharmaceutics or a similar field; alternately, a combination of M.Sc in Clinical Pharmacology, or similar field + Pharm.D. with relevant experience will be considered.
  • Significant experience with respiratory and immunology development (P1-PIV), including expert knowledge in clinical pharmacology applied to respiratory & Immunology as well as experience with regulatory filings.
  • Solid experience with line management and leadership of skilled professional scientists.
  • Externally recognised as a key opinion leader in clinical pharmacology applied to clinical pharmacology, in addition to an extensive publication record in high-quality and high-impact journals.

Desirable in the role:

  • An ideal candidate will possess 14+ years’ experience in drug discovery and development.

We strongly believe that everyone contributes with a unique set of competencies. Your curiosity and passion for personal development combined with support from colleagues, mentors and leaders, will ensure you maximise your skills, abilities and contribution.

Why AstraZeneca?
Join the team that follows the science unlike anywhere else. This is the place for curious minds. Dig deep into the biology of complex disease and uncover breakthroughs. Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

Come and join our journey – welcome to apply today! We look forward to get to know you better – please send your application to us no later than 30th April 2023.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Our Cambridge site: https://www.astrazeneca.com/our-company/our-locations/cambridge.html
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html

This position entitles competitive salary and benefits package on offer.

Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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