Group Leader, Drug Discovery - Dermatology

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time


Build a long-term career by unlocking opportunities for lifelong learning

Build unrivalled capabilities in a place that promotes learning agility and offers development opportunities. We never stand still so you’ll have the chance to constantly grow your abilities, skills and knowledge. Here we are a fusion of challenging and interesting work, in an energising and inspiring environment.

Who we are

Naturally curious, we are forever connecting and collaborating. Uncovering new insights that equip us to challenge convention and push the boundaries.

What we do

We work independently or in partnerships to deliver the next wave of science and address unmet medical needs.

The vision of AstraZeneca Early Respiratory & Immunology (Early R&I) is centered on delivering life-changing products that advance world health and help fight and cure disease. Early R&I is one of three main therapeutic research areas within AstraZeneca that deliver candidate drugs into late-stage clinical development. Here, you’ll have the opportunity to make a difference in people’s lives every day.

As a part of building the Asthma and Skin Immunity Bioscience team within Early R&I department, we are seeking a highly motivated Team Leader to lead the group of scientists and associate scientists focusing on identifying and validating new drug targets for patients with Dermatological diseases. The group will deliver key data to projects across all phases of the drug discovery and early development and work with different modalities such as small molecules, biologic molecules, peptides, gene and cell therapy. The position is placed in Cambridge, UK.

Main Duties and Responsibilities:

In this role you will be a program and people leader in the Bioscience, Asthma and Skin Immunity team focusing on developing therapeutics for treatment of dermatological diseases. The candidate will ensure delivery of preclinical and translational data in support of key portfolio program milestones, drive identification of novel targets partnering with multiple functional teams and external collaborators, drive technical excellence in bioscience research and contribute to the strategic direction of Bioscience Asthma and Skin Immunity leadership team. You will take an active role in growing and developing team members and recruitment of new talents.

  • Drive new target identification strategies and oversee the design and execution of bioscience in vitro and in vivo experiments integrating both disease and pathway approaches in support of portfolio programs

  • Develop and lead collaborations with disease experts

  • Work closely with key leaders in partner functions to ensure project goals are met

  • Select, develop, coach, mentor, retain, motivate and inspire team members in Bioscience, Asthma and Skin Immunity team

  • Accountable to manage resources effectively, providing flexible, competent and responsive Bioscience support to projects

  • Accountable for long-term development of the Bioscience department in close collaboration with the Head of Department and the other Bioscience team leaders

  • Drive innovation and scientific excellence in Bioscience through internal scientific development, external collaborations, publications and competitive awareness. Will also actively search, establish and manage external collaborations

  • Create and maintain a work environment in which scientific challenge and innovation are maximized

  • May present specific target ideas to target review meetings, leadership team and Research Board

  • Work collaboratively with other teams within and outside of Early Respiratory and Immunology

  • Make AstraZeneca scientifically visible by publishing scientific papers and presenting data at conferences

  • Strong focus on managing performance and setting challenging, achievable and measurable objectives and manage salary and bonus for the team

  • Ensure that the work of the team is performed with the right quality in accordance with compliance processes.

  • Ensure compliance with all corporate guidelines and rules

Essential Requirements:

  • M.D, Ph.D or M.D./Ph.D degree in immunology or relevant research area

  • Track record of scientific excellence in dermatology

  • Experience with in vitro and in vivo skin and immune cell models

  • Strong leadership capabilities with emphasis of people management and development of others

  • Expertise in drug discovery projects in the dermatology field or a closely related field of biology is preferred

  • A strong understanding of Immune-mediated dermatological diseases is essential

  • Training in T-cell and innate immunity is an advantage

  • Experience in the identification and progression of novel drug targets and pathways

  • Outstanding team working skills and a proven track record of working collaboratively to ensure scientific excellence and rapid progression of projects

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

So, what’s next?

Are you already imagining yourself joining us? Good, because we can’t wait to hear from you!

Date Posted


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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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