We are looking for an Associate Principal Scientist to join our Biologics Engineering (BE) team based in Granta Park, Cambridge UK. BE is responsible for the discovery and optimisation of biological candidate drugs across all AZ therapy areas such as oncology, respiratory and inflammation, cardiovascular, renal and metabolic diseases. We are constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for the development of in-house biologics discovery platforms and novel drug modalities to address unmet medical needs.

ABOUT ASTRAZENECA

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.

SITE DESCRIPTION

Granta Park Cambridge, UK is one of over 400 sites here at AstraZeneca, providing an environment where everyone feels comfortable and able to be themselves is at the core of AstraZeneca’s priorities, it’s important to us that you bring your full self to work every day. To help you maintain your best self, here’s a sneak peek into some of the things this site provides for you… Granta Park has a newly built gym with swimming pool, nursery and central food hub accessible to staff as part of the science park facilities. We also have our own bistro and deli in the AstraZeneca buildings. There are regular ‘Lunch & Learn’ events and after work socials with snacks and drinks on the last Friday of every month. This is our biggest and most spacious lab site in Cambridge…come and join us! In 2023, BE will be moving to the new AZ state-of-the-art Discovery Centre (DISC) located on the Cambridge Biomedical Campus.

BUSINESS AREA

BE is responsible for discovering and optimizing biological candidate drugs across all AZ therapy areas such as oncology, respiratory and inflammation, cardiovascular, renal, and metabolic diseases.

What you’ll do

As a lab-based scientist specialising in assay development and biologics screening, you will perform a pivotal role in delivering drug discovery and technology-based project goals to timelines and budget. As an expert in the field of assays, you will also lead assay training, contribute to development of assay best practices and strategies aligned with Biologics Engineering/disease therapy needs, and drive assay innovation through internal and external collaborations.

• Contribute independent lab-based assay expertise to develop high quality biochemical and cell-based assays for use as biologics screens and pharmacological characterisation of biologics for drug discovery or technology development projects

• Contribute to the development of assay strategies that support drug discovery delivery and technology development initiatives

• Recommend and lead development of new assay, screening and automation technologies and processes

• Maintain a well-developed understanding of approaches to assays and biologics drug discovery and apply a broader functional knowledge to support department initiatives

• Provide recommendations and creative solutions to complex assay, technology or drug discovery project problems

• Lead and provide input to peer reviewed publications, patents and participate at international conferences

• May provide general supervision and mentorship to other scientists and associates through matrix management

• Recognised internally and externally as a specialist in their area of expertise. Establish internal and external contacts and collaborations within scientific field of value to the business and present findings at internal (intra- and inter-departmental) project team and function meetings

• Ensures own work, and work of peers, is compliant, following Good Laboratory Practice, Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations

Essential for the role

• PhD with relevant experience or BSc/higher degree with equivalent lab-based experience

• Significant experience in the pharmaceutical industry and biologics drug discovery process

• Significant experience and in-depth technical knowledge of assay development and screening with a dedication to quality and scientific rigour

• Extensive experience in leading and troubleshooting biologics development strategies

• Ability to tackle challenges creatively and contribute to technology and process advancement

• Experienced in presenting complex scientific results to a varied audience

• Strong team-player with good communication skills and experience of working in multi-disciplinary teams.

Desirable for the role

• Experience in devising or contributing to team/departmental strategy

• A history of successful project delivery and publications, and patents

Why AstraZeneca?

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

Close date: 02/05/2023

Competitive salary and benefits

So, what’s next?

• Are you already investing yourself in joining the team? Good, because we can’t wait to hear from you.

• Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available, and we hope it’s yours.

• If you’re curious to know more we'd love to hear from you

Where can I find out more?

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Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.