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Associate Director - in vivo pharmacology, Bioscience, Oncology R&D

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time


You will be a Bioscience leader in the in vivo pharmacology team within a matrix management environment and have responsibility for diverse scientific activities including profiling novel agents through to proof of concept. You will work with a team of multidisciplinary scientists that are able to support oncology in vivo PK/PD and efficacy modelling studies. You will work across groups to manage/ support projects to impact on the AZ oncology pipeline.

About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.

Site description

This role will be located on the Cambridge Biomedical Campus, this site combines outstanding biomedical research, patient care and education on a single site location in the heart of Cambridge. The office will be within walking distance of the new purpose-built building that will bring together the company’s research and development activity in a brand new strategic R&D centre and global corporate headquarters. The building has been designed with the open architecture reflecting AstraZeneca’s approach to research. Open laboratories and glass walls will enable new ways of working across teams, whilst a central courtyard will put science on full display.

Business area

In the Oncology Business Unit we relentlessly follow the science, challenging the status quo to deliver more effective treatments to patients in need. Our dedication means we purposefully push back the limits of knowledge to change the practice of medicine. To ensure no patient is left behind, no matter what stage of disease. Fast-paced, it takes agility and responsiveness to stay committed in our pursuit of excellence. We work with focus to seek the unanswered questions – innovating, challenging accepted norms, quick decision-making and taking smart risks. A place of trust, it’s an opportunity to take accountability, be brave, speak up, step up and redefine Oncology, now and in the future. This is the time to join the team who is confident that cures for cancer are within our grasp.

What you’ll do

  • Lead a team of in vivo pharmacologists handling the performance of team members, helping to set goals and objectives while being responsible for team member’s professional development.

  • Act as lead in vivo biologist on drug discovery projects. In this role you will drive the in vivo strategy and design, in addition the choice of in vivo models to support drug discovery projects

  • Contributing to strategies and defining objectives to ensure the in vivo pharmacology group optimally delivers against broader AstraZeneca goals and objectives.

  • Maintain an understanding and awareness of internal and external developments that could affect the discipline and share this with team members. Identifying new drug development opportunities and conveying ideas to team members to cultivate a working environment that promotes science and encourages innovation on drug discovery projects.

  • Building networks with other team leaders and external experts to learn about new developments, demonstrating opportunities and share best practices.

  • Ensuring that your own work and the work of your team is of a high ethical standard and complies with good laboratory standards, Safety Health and Environment standards and all other relevant internal and external regulations.

Essential for the role

  • A PhD in oncology or equivalent experience in a relevant area of cancer biology

  • Extensive experience within the pharmaceutical industry and the drug discovery process across different project stages.

  • Ability to be an effective leader within multidisciplinary teams.

  • Extensive line management experience

  • Strong understanding of preclinical PK/PD/efficacy relationship modelling and generation of in vivo disease modelling data. Expertise in a wide range of Oncology models.

  • Experience providing innovative solutions to complex problems within drug discovery projects.

  • Broad and comprehensive understanding of most areas of oncology.

  • Known reputation within the industry and strong publication record.

  • Requires a thorough understanding of therapeutic needs and therapies in the disease area.

  • Excellent organisational and communication skills.

Desirable for the role

  • Experience of HO legislation and associated governance (HO Modules A-D)

Why AstraZeneca?

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society.

So, what’s next?

  • Are you already considering joining the team? Good, because we can’t wait to hear from you.

  • Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available, and we hope it’s yours.

  • If you’re curious to know more we'd love to hear from you

Competitive salary package and benefits

Close Date: 14/08/2023

Where can I find out more?

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Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.