Patient Safety, Evidence Synthesis Lead
Job Type: Full time
Locations: Mississauga, Luton, UK, or Barcelona
At AstraZeneca, we pride ourselves on crafting a collaborative culture that champions knowledge-sharing, ambitious thinking and innovation – ultimately providing employees with the opportunity to work across teams, functions and even the globe.
Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week. Our head office and BlueSky Hub in downtown Toronto are purposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects.
Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca a great place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking ambitious action to tackle some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention.
Do you have expertise in, and passion for systematic reviews and critical appraisals of evidence? Would you like to apply your expertise to evaluate the safety of medicines in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you! At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.
The Patient Safety, Evidence Synthesis Lead is a scientifically driven vital position, accountable for driving scientific and operational aspects of systematic literature reviews for post marketing commitments and contextualisation projects, including rapid reviews and critical appraisals to support various pharmacovigilance and regulatory activities.
The incumbent will work closely with cross-functional internal partners across Global Patient Safety, Global Regulatory, Global/Local Medical, and R&D to develop strategic plans for delivering systematic reviews. They will also be the go-to person to provide scientific guidance, expertise and training in systematic reviews, including to senior leaders, and collaborate with senior colleagues and peers to ensure optimal management of all evidence synthesis projects.
The Patient Safety, Evidence Synthesis Lead must be able to
1. Design and develop protocols for different types of high-quality evidence reviews, including rapid reviews, scoping reviews, systematic reviews of trials or observational studies and meta-analyses.
2. Deliver and assess different types of high-quality evidence reviews that focus on patient safety, including designing search strategies, screening studies for eligibility, data extraction, data synthesis, risk of bias or quality assessments and writing reports.
3. Conduct ad hoc literature reviews on patient safety related topics and provide critical appraisal assessments of published safety studies involving AZ products.
Ph.D. or equivalent in epidemiology, public health or related health science field with substantial experience in evidence synthesis. Alternatively, an MSc or MPH with substantial experience in systematic reviews and evidence synthesis.
Hands-on experience in undertaking and delivering high-quality systematic reviews and ad hoc literature reviews.
Ability to critically appraisal study designs and published studies, including experience applying critical appraisal tools and reporting guidelines to the literature.
Experience in synthesising and summarising published literature and medical information on drug and patient safety in a clinical or post-marketing environment, including the reporting of adverse events.
A passion for literature reviews, conducting and evaluating with a desire to improve the quality of evidence synthesis in drug safety.
A broad knowledge of patient safety, drug safety and epidemiology, including an understanding of medical terminology.
Ability to work effectively with internal & external experts, collaborative groups and contract research organizations (CROs).
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AstraZeneca is committed to taking every reasonable precaution to protect employees, our customers and the healthcare systems in the communities in which we serve. In an effort to protect the wellbeing of our employees and customers, full COVID-19 vaccination is an essential requirement of all positions at AstraZeneca. As such, all offers of employment will be conditional upon either (i) proof of full COVID-19 vaccination or (ii) proof of need for accommodation under relevant human rights legislation, and AstraZeneca’s determination that the requested accommodation can be provided without undue hardship. You will be required to submit proof of full vaccination or proof of need for accommodation during our background screening process.
AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.