Scientist, Bioscience - Dermatology (10 months fixed term contract)
Job Type: Full time
Be empowered to be innovative and creative where difference is valued
Join a place built on innovation and creativity. Where different views and perspectives are welcomed and valued. An environment that champions inclusion, and teams that reflect the diversity of the communities that we serve.
About AstraZeneca in Cambridge, UK:
At AstraZeneca, we believe in the potential of our people and you’ll develop beyond what you thought possible! We make the most of your skills and passion by actively supporting you to see what you can achieve no matter where you start with us.
Summary of the group:
The Respiratory & Immunology Bioscience Asthma and Skin Immunity group, sitting within AstraZeneca Research and Early Development, is a dynamic and enthusiastic group aiming to identify new therapies for skin and lung diseases. We are driven by science and the need to offer new therapies that improve the lives of patients with debilitating diseases. This is a great opportunity to join in our effort to develop new therapies for skin diseases and make a difference to people’s lives every day.
Key Responsibilities and Accountabilities:
We are looking for a motivated new member of the team, able to learn and grow in our organisation. The successful candidate will provide laboratory support for ongoing projects in dermatology.
Working independently with minimal supervision, as well as part of a team, you will support basic research and drug projects by performing and optimising assays
A team player able to collaborate on multiple projects with scientists from a variety of functional teams
Accurately record and assess all data generated in course of analyses through preparation of protocols and electronic lab book write-ups with a high attention to detail
Ensure that work is performed in accordance with appropriate Safety, Health & Environment (SHE), quality and compliance standards
Solve technical and logistical challenges
Communicate effectively with line manager and team
Education, Skills and Qualifications:
PhD in immunology or BSc (or equivalent) Immunology or relevant field with a minimum of 4 years relevant laboratory experience
Strong immunology background
Isolation of primary cells (PBMCs and T cells) from human blood and/or immune cells from tissue
Expertise in primary human cell culture including co-culture models (e.g. dendritic cells and T cells), expertise in multi-panel FACS, including both intracellular and extracellular cell surface markers.
Strong hands-on skills in basic biochemical and molecular techniques including quantification of mRNA (qPCR) and protein expression; ELISA, Western blot.
Experience with data organization and basic statistical analysis
Demonstrate strong organisation, record keeping and communication skills
Experience with one of the following areas would be advantageous but is not a requirement
Experience working in dermatology target validation and/or screening for drug discovery
Single cell RNA sequencing or TCR sequencing (wet lab sample processing, running 10x)
Use of CRISPR for gene editing
At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
So, what’s next?
Are you already imagining yourself joining us? Good, because we can’t wait to hear from you!
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.