Global Head of Enterprise Architecture

AstraZeneca UK

Location: Cheshire East, Gaithersburg, Maryland

Job Type: Full time


Global Head of Enterprise Architecture

Gaithersburg (USA), Macclesfield (UK) or Gothenburg (SWE)

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and fuel your entrepreneurial spirit.

Technology at AstraZeneca is a home for purposeful disruptors!

Here our work has a direct impact on patients – transforming our ability to develop life-changing medicines. We empower the business to perform at its peak and lead a new way of working, combining ground breaking science with leading digital technology platforms and data. All with a passion to impact lives through data, analytics, AI, machine learning and more.

In Architecture, we connect the dots across the business to improve the agility and functionality of our processes to accelerate AstraZeneca to the next level. There’s so much potential to influence and inspire change, it’s a big challenge if you’re up for it.


Strong Enterprise Architecture is the cornerstone of our Digital Transformation and fundamental to delivering on our AZ Ambitions and IT2025 Strategy. As the Senior Director Enterprise Architect you will be responsible for defining a world class enterprise architecture to meet the current and future needs of AstraZeneca and our broader ecosystem. You will lead a newly formed central team of Enterprise and Solution architects in defining the enterprise wide target state architecture, identifying innovative solutions, laying out the technology roadmap and supporting implementation projects.

This target state and roadmap will guide technology investment planning to reduce TCO and improve operational performance. The role is critical to the successful delivery interoperable solutions, reduction of technical debt and development of an enterprise wide integrated platform strategy.


Establishing Architecture as a strategic capability with deep thought leadership in the use of technology for competitive advantage and defining modern Architecture Strategy that supports our business architecture.

You will lead the transformation of AZ architecture & capability, into a fit for future organisation focused on upcoming technology trends, being thought leaders on next generation application / infrastructure, with strong external relations with other companies and leading Tech partners

Setting the Enterprise Architecture vision, strategy and mandate, aligned to business objectives and capabilities and driving the cultural change needed across AZ to move to an integrated architecture

You will understand and incorporate new technology trends to drive value for our business and improve patient outcomes

Delivering and maintaining Architectural Diagrams and ownership of CMDB, defining the artefacts, tools and technologies to support the effective delivery of architecture & implementing an Enterprise Reference model will all be part of your role, along with ensuring appropriate governance forums are in place

You will drive effective engagement across the IT organisation, SET Functions and other key stakeholders


  • Proven experience in driving an integrated architecture that is based on business architecture
  • Demonstrated experience leading a transformation to a platform architecture in a large scale, multi-national company
  • Team Leadership – proven experience in managing diverse, global teams with ability to provide direction, understand resource capability and successfully drive results working with direct reports, dotted line and/or internal or external resources
  • Demonstrable experience of coaching and mentoring an architecture team, protecting, growing, evolving and winning through others
  • Proven experience of leading change and cultivating new ways of working across an organisation and driving adoption of solutions
  • Relevant technical degree or equivalent


We’re a network of entrepreneurial self-starters who contribute to something far bigger. There’s a diversity of expertise in our Technology group that’s unique to AstraZeneca – it allows us to dive deep into exploring new leading-edge technology. We enable AstraZeneca to perform at its peak by delivering world-class technology and data solutions. Our work unlocks the potential of science. We optimise and evolutionise AstraZeneca by maximising efficiencies and finding new ways to drive productivity. From automation to data simplification. We’re not afraid to take ownership and run with it. Empowered with unrivalled freedom. A place to be open and transparent – we speak up, think creatively and share ideas. Our diverse contributions help us to make better decisions. But we have a constant drive to innovate, and an appreciation for high standards. It takes challenging the status quo to add value in our ever-evolving environment. We love it here because put simply, we make a meaningful impact.


Are you already imagining yourself joining our team? Good, because we’d love to hear from you! Click the link to apply and we’ll be in touch as soon as we can.

Competitive salary & benefits on offer.

Open Date: 25/05/23

Close Date: 22/05/2023

Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

You’ve got this!