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Tumour Portfolio Director, OBU Medical Affairs

AstraZeneca UK

Location: Cambridgeshire, Gaithersburg, Maryland

Job Type: Full time


At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most demanding situations because we are committed to doing the right thing. We put patients first and follow the science to bring life-changing medicines to patients that need them.

We are currently searching for a candidate who can drive strategic planning and execution of the OBU projects and accountabilities for the OBU Medical organization which includes interface at a franchise level with cross-functional teams across OBU. The role would include project oversight and budget management, change management, and cross-functional coordination with other franchise medical teams. This role would report directly to the Strategy, Operations & External Innovation Leader for OBU Medical but would work closely with the franchise lead. The position will be based in Gaithersburg, MD (USA) Mississauga or Cambridge UK.

The ideal candidate will be expected to work in a highly effective way with other project and medical leaders to develop integrated plans which can be delivered globally and across cross-functional boundaries. The ideal candidates can demonstrate their strategic thinking, problem solving skills, ability to work collaboratively and act decisively to support the broader goals of OBU Medical as a whole.


  • Supports the Tumour Head/Teams to progress from ideation to implementation on the portfolio tumour strategy synergistically across indications and assets and optimizes global and local interfaces for execution

  • Facilitates overall budget and strategic workforce planning across the functional groups including forecasting, phasing and prioritization across the business planning cycle as well as rollup into Long Range Plans (LRPs)

  • Responsible for strategic planning and prioritization of key franchise team deliverables such as development of Medical Plans, Evidence Generation plans, Confidence/Evidence concept proposals, Launch plans Congress plans, and Scientific exchange plans

  • Facilitates Externally Sponsored Research Review committee meeting for timely review and decisions on proposals

  • Collaborates with Medical Affairs tumour teams to facilitate compliant external grant requests review and decision making

  • Maintains project / deliverables dashboard for portfolio progress against scorecard objectives and represents updates in monthly GMA operational meetings

  • Accountable for implementation of medical standards to ensure compliant functioning of the organization

  • Leads effective agenda driven meetings with leadership team, provides strategic input into meeting agendas, identify and track decisions and actions for the team to monitor progression of activities

  • Defines with Tumour Head required offsite meetings and ensures flawless implementation in coordination with other relevant functions

  • Co-ordinates and assists Tumor Head in preparation of presentations to senior leadership and communications on key topics and initiatives

  • Continuous improvement on ways of working to share best practices to streamline and simplify the business processes

  • In this role, you will be entrusted with the responsibility of overseeing and guiding a specialized team operating within the Oncology Business Unit. Your leadership will play a pivotal role in steering the team towards success and ensuring the effective execution of projects and initiatives related to oncology products and services.

  • Manages and trains indication/asset PMs, assign specific project responsibilities and create a high performing team by building trust and providing mentorship

  • Partners with indication/asset level project managers to ensure efficient functioning of the Medical Implementation Teams and ensure connectivity with Integrated Business Teams


  • Encourage a vibrant, entrepreneurial and externally facing team focused on the delivery of successful projects and programs that support courageous leadership, innovation and collaboration

  • Collaborate strongly with other Project Leaders to embed best practice

  • Flexible mindset and dedication to efficient productivity

Required experience:

  • Minimum of 7 years experience in pharmaceutical industry

  • Minimum of 3 years experience in Medical Affairs, Commercial and R&D (Global, regional, or local)

  • Comprehensive understanding of the development and commercialisation of pharmaceutical products

  • Experience of successful influencing cross functionally, cross-culturally and cross-brands

  • Experience of effective working in a multi-cultural, matrixed environment

  • Experience working in a global setting, managing stakeholders within different time zones

  • Experience preparing and/or delivering presentations to executive leadership

  • Experience in planning and leading strategic initiatives

Preferred Requirements:

  • Graduate level degree in sciences or business degree

  • Six Sigma Medical/Process Excellence and/or Project Management/PMP/FPX certification is a plus but not required

  • Depth of understanding of medical, scientific and/or commercial pharmaceutical marketplace of Oncology

  • Consulting experience


  • Skilled in organisational change including process development and implementation, people development, organizational effectiveness, and communication

  • Able to deliver high quality work outputs despite ambiguity or a constantly evolving environment

  • Delivery focus with an ability to be responsible for and manage multiple project deliverables in very short timelines

  • Interpersonal skills with an ability to display a variety of leadership styles dependent upon the situation

  • Evidence of the ability to pull together diverse teams over whom they have no line management responsibility in a matrix environment (i.e. Ability to influence and drive for results)

  • Demonstrated knowledge and very wide understanding of global business context

  • An excellent communicator; evidence of strong independence and innovative seeker of strategic solutions; forward looking

  • Strong leadership attributes to clarify strategic direction, generate commitment, balance short and long-term needs, resolve differences constructively, and reinforce expectations

  • People management of indication level project managers to drive synergies and efficiencies across the portfolio

Date Posted


Closing Date


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.