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Senior Global Medical Affairs Leader - Diagnostics - Breast

AstraZeneca UK

Location: Cambridgeshire, Gaithersburg, Maryland

Job Type: Full time


Do you have expertise in, and passion for Medical Affairs in Oncology? Would you like to apply your expertise to impact the Sr Global Medical Affairs Leader - Diagnostics role in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

AstraZeneca’s vision in Oncology is to help patients by redefining the cancer-treatment paradigm, with the aim of bringing six new cancer medicines to patients between 2013 and 2020. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and hematological cancers. As well as other tumor types, these are being targeted through five key platforms - immunotherapy, the genetic drivers of cancer and resistance, DNA damage repair, HER2 and antibody drug conjugates, underpinned by personalized healthcare and biomarker technologies.

AstraZeneca is seeking a Senior Global Medical Affairs Leader, Diagnostics, to join our breast cancer franchise team. This role reports to the Global Medical Breast Cancer Franchise Head.

The Diagnostic Senior GMAL ensures the timely, high quality input into global medical and lifecycle plans, to support optimal in-market companion diagnostics / testing solutions that enable optimal patient identification that informs treatment choices and support patient access to the right drugs at the right time.

An important element of this role is therefore to develop strategic and long-term partnerships with relevant external oncology and pathology stakeholders and decision makers, through the development of AZ’s scientific leadership with advocacy, scientific organizations, thought leaders and HTA/payers organizations to help inform and develop the best in class diagnostics and biomarker testing capabilities aligned with the medical needs of our portfolio.

This role will require broad internal cross-functional collaboration and matrix leadership, with multiple medical, translational, and diagnostic development teams, as well as teams in key markets. Based on a deep scientific understanding of the pathology/micro-environment of the tumor, as well as the clinical issues associated with testing environment and pathology workflow, you will enable the organization to help develop tailored biomarker testing solutions for our portfolio of targeted therapies for breast cancer.

You will also be responsible for the coordination of all Medical Affairs activities related to diagnostics and biomarker testing in Her2+ diseases and Breast Cancer overall , including science advisory boards, alignment of the publication plans, and medical evidence generation plans, providing appropriate input into the global externally sponsored research collaborations and other medical affairs activities.

Finally, you will contribute to the broader strategic planning to build Astra Zeneca's medical leadership in breast cancer, and deliver medical insight into the development and execution of the overall breast cancer strategy.

Essential Requirements

  • Advanced scientific degree (MD, PhD, PharmD)

  • 7+ years of experience in health care delivery; preferably oncology diagnostic or clinical lab experience, pharmaceutical experience is a plus Significant knowledge and experience in Diagnostics/Assay development and method evaluation

  • Understanding of drug development and commercialization processes including understanding of health economic outcomes research/payer access issues

  • Proven ability to generate, analyze and interpret clinical trial and published data

  • Proven ability to develop and execute diagnostic-focused clinical/ RWD trials

  • Track record of successfully developing and executing Scientific Plans both in terms of evidence generation, scientific communications and external expert engagements

  • Ability to manage multiple projects and products simultaneously to ensure timely, on-target and within budget accomplishment of tasks

  • The candidate is expected to have strong project management skills and ability to work

  • Excellent communication and presentation skills in English

Desirable Requirements

  • Global Pharma experience

  • Global product launch experience

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.