Associate Principal Scientist – Modelling & Simulation

Location: Macclesfield – UK; Gothenburg – Sweden

Competitive Benefits & Salary

Closing Date: 11th October 2023

Pharmaceutical Technology and Development (PT&D) is the organisation that turns brilliant science into medicines that help millions of people. We work across the entire value chain, crafting and delivering active ingredients, formulations and devices for new medicines and providing expert technical support to all AZs commercial drug substances and products to ensure we optimally supply medicines to patients. The Digital Science organisation, sits within Pharmaceutical Technology and Development, where we focus on development of digital strategy, new tools and technologies. Working collaboratively with functions, IT and external partners to transform the way they deliver drug substance and drug product Process Development. The Digital Science organisation has recently centralised Modelling & Simulation skills to create a strategic global team of experts covering a wide range of Modelling & Simulation expertise, with members based in Gothenburg, Sweden and Macclesfield UK.

What you’ll do

In this role you will work collaboratively with a variety of scientific specialists and project managers across a global organization to optimally deliver sophisticated engineering modelling solutions and play a key role in crafting and driving the Modelling & Simulation strategy. The role holder will typically:

• Translate sophisticated pharmaceutical process problems into appropriate mechanistic/first principles models and deliver timely solutions

• Work collaboratively with experimentalists with different backgrounds to identify Modelling & Simulation opportunities and to strategically direct experimentation

• Drive and champion the organizational digital transformation

• Establish strong working relationships with the Modelling & Simulation team members and with other colleagues across pharmaceutical Development and technology to enable an impact-driven application of Modelling & Simulation

• Develop, validate and implement Modelling & Simulation workflows to be used by the wider scientific community

Crucial for the role

• A solid scientific background. MSc/PhD in chemical engineering, mechanical engineering or similar discipline, ideally with specialism in process modelling

• A solid knowledge of the science behind process models, and experience of developing/applying process models for development of industrial products and processes

• Strong expertise in relevant programming and scripting languages, e.g. Matlab, Python, or similar, and a willingness to learn

• Experience of using simulation tools including gPROMS, Aspen, ANSYS, etc

• Strong collaboration, communication, influencing and networking skills

• Cultural awareness

Desirable for the role

• Working experience in the pharmaceutical/biopharmaceutical/food/cosmetics and personal care/fast paced consumer goods industry

• A broad knowledge of process equipment and process technology

• Ability to proactively apply novel modelling approaches to deliver value in the development and manufacturing of pharmaceutical drug products

• A rational approach to problem solving, and an ability to make judgements based on sound reasoning

• Track record of scientific publications in the Modelling & Simulation area

Why AstraZeneca?

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

Be encouraged into our inclusive network of diverse and high performing teams. Have the support, trust and respect to thrive here – fair leadership, great workplaces and energised teams who always have each other’s back. For those with a shared drive and passion for impacting people’s lives, experience a sense of belonging like no other.

What’s next!

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you

Where can you find out more?

Our Social Media, Follow AstraZeneca on LinkedIn

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We encourage and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on inclusivity in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.