Senior Analytical Scientist - 12 month fixed term contract

Cheshire East
Full time
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AstraZeneca UK
Healthcare & medical
10,001+ employees
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Senior Analytical Scientist - 12 month fixed term contract

Macclesfield, UK

Salary & Benefits Competitive

At AstraZeneca, you will be empowered to be innovative and creative where difference is valued. We thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people's outstanding skills with those of people from all over the globe.

We are currently looking to recruit Senior Analytical Scientists with scientific project based experience into roles in chemical development. You will join our Early Chemical Development (ECD) team in Pharmaceutical Sciences, Macclesfield Campus, UK. Within this group, we transform science into medicines that help millions of people. We are dedicated to the development of pre‑clinical and early clinical active pharmaceutical ingredients (API) across a range of molecules, and our key skill areas include Analytical Chemistry, Crystallisation, Isotope Chemistry, Large-Scale Laboratory (Kilo-Lab) Manufacturing, Process Chemistry, Process Design, Process Engineering, Route Design and Separation Science.

Role specifics

This is a laboratory based role, and we are looking for expert scientists who have a background in Analytical Chemistry, with hands-on experience of analytical development, and who are familiar with the latest analytical techniques utilised in a pharmaceutical development environment.

Typical Accountabilities

  • Leading Active Pharmaceutical Ingredient (API) analytical activities within cross-functional project teams to support project progression during the early pre-clinical and clinical development phases
  • Development of robust analytical methodologies supporting the development of synthetic routes and processes and the release and stability analysis of API
  • Providing technical leadership to the manufacture of intermediates and API for pre-clinical and clinical use
  • The development of API analytical control strategies, keeping a strong focus on quality for our patients
  • Planning and execution of lab-based experimental work in accordance with project timelines
  • Assessing, reviewing and reporting data from own work and work of junior colleagues, and interpreting findings and drawing authoritative conclusions and recommendations so that their significance can be appreciated
  • Management of own work to achieve drug and improvement project targets in a timely fashion and to agreed quality standards by applying technical knowledge and expertise

Education, Qualifications, Skills and Experience


  • A degree (BSc, MSc or equivalent experience) in Chemistry or Analytical Chemistry
  • Experience of analytical development in a professional environment, or a PhD with significant analytical chemistry content
  • Experience of successfully leading and delivering analytical activities
  • Knowledge and practical experience across a range of techniques, e.g. LC, MS, GC, NMR, and in analytical method development
  • Scientific leadership skills and the ability to use knowledge and experience to assess options available and deliver robust scientific contributions to projects
  • Strong problem-solving skills, underpinned by strong practical laboratory experience
  • Experience of working collaboratively within a mixed skill technical team and ability to develop and utilise networks
  • Ability to communicate complex scientific information in a clear, concise and understandable way


  • Broad experience and a proven track record within an analytical department in a pharmaceutical or similar research/manufacturing industry
  • Experience with technical analytical outsourcing of drug substance development and manufacture activities at CDMOs
  • Experience of delivering CMC content or contributions, based on analytical activities, to regulatory filings for pharmaceutical products within the clinical development phase
  • Knowledge and practical experience of quality and regulatory requirements (GMP and ICH) and health and safety requirements

So, what's next?

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you!

To be considered for this exciting opportunity, please complete the full application at your earliest convenience - it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.

Welcome with your application no later than 14th June

Where can I find out more?

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.