Associate Director Clinical Pharmacology and Quantitative Pharmacology (CPQP) in Vaccines and Immune Therapies, Neuroscience & Clinical Immunogenicity

Cambridge UK, Gaithersburg MD, US

Make a more meaningful impact to patients’ lives around the globe

With our ground-breaking pipeline, the outlook is bright. Be proud to be part of a place that has achieved so much, yet is still moving forward. There’s no better time to join our global, growing enterprise as we lead the way for healthcare and society.

Be encouraged and supported to think creatively in our dynamic environment. Here we are free from fear of failure, free to ask the right questions and make bold decisions.

Within the Clinical Pharmacology and Safety Sciences function, we have a state-of-the-art quantitative clinical pharmacology group with a diverse and uniquely skilled team of clinical pharmacometricians and clinical pharmacology scientists. Cambridge and Gaithersburg are key research and development locations for our Vaccines and Immune Therapies, Neuroscience & Clinical Immunogenicity area.

What you will do:
You will work closely with clinical pharmacometricians, physicians and other scientists, and apply your expertise and leadership skills to contribute to the strategy of the clinical program and the design and interpretation of clinical studies. You will influence key decisions in early and late phases of clinical development.

In collaboration with clinical pharmacometricians, you will represent Clinical Pharmacology and Quantitative Pharmacology in cross-functional project teams, and take responsibility for developing the clinical pharmacology strategy.

The work includes integration of relevant data, such as dose information, pharmacokinetics, biomarkers and clinical endpoints within and across studies, compounds and development stages. You will take part in identifying opportunities to apply model informed drug development to accelerate and inform decision making. You will communicate your findings within and outside of AstraZeneca and publish in peer reviewed journals.

Essential Criteria

• PhD or equivalent (M.Sc/Pharm.D.) level expertise in a relevant field
• Industry experience or equivalent in pharmacokinetics and clinical pharmacology aspects of drug development
• Experience of writing and reviewing clinical trial protocols and reports and regulatory documents such as INDs, IBs, NDAs or BLAs
• Knowledge of pharmacokinetics, its clinical application and regulatory context
• Knowledge and experience in use of PK and PKPD modeling applied to life sciences
• Biological understanding of disease and drug action

Desirable Criteria

• Track record in creating and delivering on clinical pharmacology strategies of both small and large molecules.
• Recognised clinical pharmacology expertise demonstrated by scientific publishing in the field of clinical pharmacology.
• Early and late phase clinical development experience.

Why AstraZeneca

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

So, what’s next?

Complete your application before the below closing date.

This role is open from 23/05/2022, we welcome your application no later than 20/06/2022

Where can I find out more?

Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca has taken critical steps to protect colleagues, loved ones, and patients from COVID-19 and its variants. Accordingly, AstraZeneca requires all US employees to be fully vaccinated for COVID-19 prior to the first date of employment. AstraZeneca will consider requests for reasonable accommodations as required by applicable law.