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Scientist, Cell Engineering


Location: Waltham, Massachusetts

Job Type: Full time


Company Description

For over 20 years, Abcam has been providing tools the scientific community needs to enable faster breakthroughs in critical areas like cancer, neurological disorders, infectious diseases, and metabolic disorders.

We believe that to continue making progress, we need to work together in new ways. We need your own unique perspective as well as this of our people to make an always greater impact on the world. This community needs people like you: dedicated, agile and above all audacious so we can truly bring progress forward.

Job Description

Abcam is a leading life science company experiencing exciting new growth and expanding product development within our cell lines portfolio. We are on a mission to address a major academic and industry-wide challenge: the time and effort-intensive nature of generating and validating CRISPR-modified cell lines. Join our Cell Engineering team at Abcam's Waltham office, where you'll play a vital role in providing critical research reagents to customers on a global scale, backed by Abcam's industry-leading high standards for product validation.

Position Overview:

We are looking for a Scientist/Senior Scientist (based on experience) to join our Waltham, MA team and harness our high-throughput platforms to create CRISPR-edited cell lines. In this role, you will work with cutting-edge CRISPR-Cas9/genome editing technologies, liquid handlers/automation, robotics, scheduling software, high-throughput microscopy, high-throughput next-generation sequencing (NGS), and more. Your focus will be on generating and validating various edited cell lines, including mammalian cancer cell lines, primary cells, and iPSC cells of diverse tissue origins, including immune and neurological cells. This is a unique and exciting opportunity to push the boundaries of laboratory automation and perform complex molecular biology techniques at an industry scale, all within Abcam's brand-new team.

Key Responsibilities:

  • Utilize high-throughput platforms and automation to generate CRISPR-edited cell lines.
  • Lead and manage a team of 2 junior scientists.
  • Apply cell biology, molecular biology, and NGS sequencing analysis/bioinformatics techniques.
  • Develop high-throughput/automation pipeline/workflow.
  • Contribute to global product development and expansion efforts.
  • Gain expertise in cell line engineering across a broad array of cellular models and therapeutic modalities (immuno-oncology, cancer, neuroscience, etc).
  • Collaborate within a matrixed work environment as part of a multidisciplinary cell line engineering team.


To excel in this role, you should possess a Ph.D. or M.S. in biology, genetics, engineering, or a related field, complemented by 0+ years of industry experience for Ph.D. holders or 2+ years for M.S. graduates. Your expertise lies in molecular biology techniques, encompassing DNA extraction, PCR, amplicon barcoding, library preparation, library quality control, NGS sequencing, and NGS data analysis.

Your skill set extends to the realm of laboratory automation, where you have hands-on experience with tools like cell sorters for single cell cloning, high content imagers, robotic arms, or scheduling software, all of which enhance the efficiency of your workflow. With a strong experimental background, you demonstrate a knack for automating experimental and data workflows, reflecting your keen interest in process and workflow optimization.

In addition to your technical prowess, your success in this role hinges on your ability to collaborate as a team player. You possess exceptional communication skills and the capacity to engage effectively across various disciplines and cultural contexts. Your holistic approach to problem-solving and adaptability will be instrumental in contributing to our dynamic work environment.

At Abcam, we offer an opportunity to be part of a pioneering team that is at the forefront of cell line engineering, addressing critical challenges in life science research. Our collaborative and innovative work environment fosters creativity and collaboration, allowing you to work alongside experts in the field. We provide opportunities for professional growth and development, recognizing that our employees are key to our success. Abcam offers a competitive compensation and benefits package, ensuring that your contributions are valued and rewarded. Join us in our mission to accelerate scientific discoveries and make a positive impact on the global research community. Abcam is an equal opportunity employer that values diversity, providing an inclusive and welcoming workplace for all.

Additional Information

We know that when it comes to benefits, no one size fits all. Flexibility and choice matter which is why, in addition to market competitive salaries, we offer you a flexible benefits package which is tailored to your unique needs and support your financial, physical and emotional wellbeing. This includes our award-winning share scheme, 18 weeks fully paid maternity leave, 6 weeks fully paid paternity leave as well as highly flexible working and much more. Besides, your development will be integral to your experience here. You will grow alongside other talented minds, in ways you may often find unexpected.

When people come together, incredible things happen. Here you’ll work in a safe environment where you can be who you truly are. We’ll champion and celebrate your uniqueness throughout your journey with us. This is how we excel at partnering with the scientific community no matter the challenge, ultimately helping solve the world’s most critical diseases. Find out more about Diversity & Inclusion at Abcam.