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Bioassay Development Scientist (18 months maternity cover)

AstraZeneca UK

Location: Cambridgeshire

Job Type: Full time

Posted


Are you a Life Scientist with a solid background in in vitro assay development, looking to expand your experience within the pharmaceutical industry? Are you driven by a commitment to help patients and explore the potential of science? We have an exciting opportunity for you at AstraZeneca. Join us on an 18-month fixed term contract as part of the Bioassay, Biosafety and Impurities Group. This team is responsible for developing cutting-edge methods to evaluate product quality, enabling product understanding, manufacturing process development, formulation, drug product development and regulatory filings. We are seeking a dynamic and highly motivated lab-based scientist with proven experience in in vitro biological activity methods.

Our Expectations:

  • Use your knowledge of cell culture and hands-on biological assay development in a team oriented environment
  • Support our drug development programmes with data, effectively utilising existing and novel technologies and instrumentation
  • Convert opportunities and resources to succeed and thrive around the team and communicate achievements to different audiences, including team meetings, global group meetings and matrix teams.
  • Learn from experience and guidelines/documentation to increase responsibilities and complexity of tasks to be performed with a higher level of autonomy.
  • Build on AZ’s science driven dynamic environment

Responsibilities

  • Develop biochemical and cell based potency assays based on drug mode of action and carry out routine sample testing in a timely fashion

  • Enable transfer of any methods to other groups as appropriate

  • Accurately record all data clearly and concisely with a clear understanding of its implications within the overall context of drug development

  • Manage own work to ensure that agreed targets are met and to agreed quality standards, communicating progress appropriately.

  • Discuss and defend experimental findings at cross-functional meetings, representing the Bioassay Team, as well as internal symposia and external conferences.

  • Prepare for review clear and concise technical documents like SOPs, work plans, work reports and instructional documents

  • Assist in the training of others in procedures and practices

  • Ensure that work is performed in accordance with appropriate Safety, Health & Environment (SHE), quality and compliance standards

Essential Skills/Experience:

  • Minimum BSc (or equivalent) in Immunology, Cellular Biochemistry, Cell Biology, Molecular Biology or a related field together with industry experience (up to 6 years relevant post-BSc experience) or PhD with similar academic experience (up to 2 years relevant post-PhD experience)

  • Thorough understanding of mammalian cell culture and hands-on experience with in vitro cell-based assay techniques and their applications in assessing e.g. cellular signalling, receptor binding and cytotoxicity

Desirable Skills/Experience:

  • Drug development experience in academia, Pharma/Biotech industry

  • Experience with immunoassay/binding assays

  • Experience with cell line generation and molecular biology techniques

At AstraZeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before.

Join us in our Biopharmaceuticals R&D division and be part of a dedicated Research & Development team. Strengthen our pipeline to make a meaningful impact on patients. This is the place to go beyond discovery. We think holistically about patients and are always learning from those living with diseases. We harness digital, data science & AI to fast-forward our research. Making sure work born in a lab can make a real difference. Everyday, impacting patients' lives across the world.

Ready to make an impact? Apply now and join us in pushing the boundaries of science to deliver life-changing medicines!

Date Posted

22-lut-2024

Closing Date

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
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